SCIE 1P51 Lecture Notes - Lecture 6: Butanone, Nitrosamine, Nnk

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Neither health canada nor the fda regulate the amount of nicoine in tobacco products. Nicoine can be converted to other nitrogen containing compounds: nitrosamines known to be carcinogenic, nitrosonornicoine nnn, 4-(methylnitrosamino)-1-(2-pyridyl)-1-1 butanone nnk. Isomers diferent compounds with the same molecular formula. Stereoisomers: isomers that difer in the way the atoms are oriented in space but no in which atoms are bonded to which atoms. Nirnicoine is found in the leaves of tobacco plants: it is converted into nitrosonornicoine and 4-(methylnitrosamino)-1-(2-pyridyl)-1-1 butanone during the curing of tobacco and combusion of tobacco products, nnn, nnk come in let and right handed versions. Two forms of compound nitrosonornicoine: (s) n-nitrosonornicoine is carcinogenic (let handed form of the molecule, chiral molecule irst/ binds like a key in a lock, enaniomer, mirror image, s form. Tobacco wars: movie about the tobacco companies and the, oicers are trying to stop smoking, people are ighing against it, diferent adds that targeted young adults to start smoking.

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