SCIE 1P51 Lecture Notes - Lecture 2: Smallpox, Cowpox, Variolation

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Term paper is worth 5% of inal grade. Due week of jan 26 and feb 2. Artlce has to be january 2015 to present. They published the indings about small pox and vaccinaions. Jenner sent cowpox to his colleague john clinch for use in newfoundland. In 1950 50 million cases of small pox every year. Concerted efort by governments to have populaion vaccinated. Who program to eradicate small pox 1960 and 1970. Mass vaccinaions and reporing and tracking of disease. Oct 26th 1977 global reach of vaccinaion program so successful that the last natural case of small pox occurred in somalia. Complicaion from vaccinaion very rare but death rate is 1 in a million. Required component of vaccines since 1930: 1916 typhoid vaccine contaminated with staphylococcus aureus led to 4 deaths. Thimerosal is metabolised to ethyl mercury which is excreted faster than methylmercury. Current thimerosal containing vaccines: inluenza, meningococcal, japanese encephaliis, pneumococcal polysaccharide, diphtheria tetanus.

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