KINE 2P09 Lecture Notes - Lecture 6: Granulocyte, Insulin-Like Growth Factor 1, Natriuretic Peptide
9 May 2018
School
Department
Course
Professor
KINE 2P09
Type 1
- Pancreatic Beta cells are damaged
- Cannot secrete enough insulin
Type 2
- Impaired glucose tolerance or insulin resistance
- Obesity, high sugar diets
- Insulin is secreted but not effective at target cells
- Beta cells fail
Other endocrine Organs
- Adipose tissue
o Leptin
▪ Increase fat oxidation in muscle
- Heart
o Atrial natriuretic peptide – BP
- Kidneys
o Erythropoietin
o Renin
- Liver
o Erythropoietin
o IGF-1
o Angiotensinogen
- Stomach and small intestine
o Enteric hormones
Blood
- Plasma
o Water
o Electrolytes
o Proteins
▪ Albumin
▪ Globulins
▪ Fibrinogen
o Gases
▪ O2, CO2, N2
o Waste
▪ Ammonia and urea
- Cells
o RBC (erythrocytes)
▪ Carry O2
▪ Hemoglobin
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