NEUR 2P37 Lecture Notes - Lecture 15: Midbrain, Basal Ganglia, Putamen
16 Mar 2017
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Document Summary
Addiction: an illness of motivation: motivation typically rewards us for doing things that will keep us alive, addiction twists the circuitry of motivation to reward something different from typical motivated behaviours. Why motivation matters: motivation allows the brain a way of setting priorities, motivation could be described as the ability to make predictions about what is most important in a particular scenario, motivational drives can be internal or external. Feelings: the sensory side of motivation: basic drives maintain homeostasis (energy, temperature, chemical balance etc. , the body can maintain homeostasis by autonomic responses, neuroendocrine responses, or behavioural responses. The hormones ghrelin and leptin signal hunger and satiety, respectively. Neuropeptide y acts on the paraventricular nucleus to stimulate feeding. A different (cid:374)eurotra(cid:374)s(cid:373)itter (cid:862)pomc(cid:863), acts on the arcuate nucleus to inhibit feeding: obesity is influenced by the presence of hormones: Fat mouse; has a mutation in the obese gene and is unable to produce leptin.
