HLSC 4P99 Lecture Notes - Lecture 3: Carpal Tunnel, Vise, Sarcoidosis

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For an roc test, look at the direction of the test (what makes it positive, or what makes it negative). If your roc is curve is below the reference line, the direction is wrong! Ideally, you want the roc curve to intercept that yellow circle. If your curve followed the line, you"d be a 50% accuracy. Depending upon the cut point that you pick, as sensitivity goes up, specificity goes down and vise versa. Exam: two roc curves on the same graph, compare accuracy curves. You add up the noise and you pick that number. Exam: to fore go to not do it. The example provided here presents data from a study looking at the value of angiotensin converting enzyme (ace) in the diagnosis of active sarcoidosis. In this study, ace levels in patients with active sarcoidosis who turned out not to have the disease. To help you answer this question conduct a number of exercises.

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