HLSC 3P97 Lecture Notes - Lecture 2: Multiple Drug Resistance, Opportunistic Infection, Drug Resistance
13 Feb 2018
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Document Summary
Symbiosis: intimate association of 2 species of organism living together. Obligatory - association is essential for both organisms. Mitochondria are primordial, however now they rely on humans and we need them for oxidative respiration. Parasitism: parasite benefits at the expense of the host; association is essential for the parasite. Normal human has 10^3 cody cells and 10^4 normal flora. Pathogenicity of microbiome when the balance between host and microbe is disrupted. Survival of bacteria in the presence of an antibiotic it was previously susceptible to. Superbug: bacterium that is resistant to more than one antibiotic. Anyone who gets a resistant strain, will pass on a resistant strain. C. diff - survives very well on bed rails, mattresses etc. so unless healthcare workers are absolutely obsessive, they can spread it. Bacteria has a mutation that allows it to break down the antibiotic. Bacteria has a mutation that alters the antibiotic so that it doesn"t fit in the intracellular receptor.
