HLSC 2P49 Lecture Notes - Lecture 10: Coronary Artery Disease, Trans Fat, Red Meat

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Faty deposits (plaques) build up on vessel walls. Inlammaion response imparial too (contribute to plaque build up and blockage) Plaque may break free and block or roughen or damage vessels, platelets form clot and block if block, brief/parial cramp angina pectoris. Gender men more vulnerable at younger ages, but older woman at high risk too (why younger men at risk premenopausal women with higher estrogen levels protect them, men also engage in riskier lifestyles) Ethnic/cultural factors france & japan lower rates (more seafood omega-3 faty acids, more red wine resveratrol/polyphenol) Ex. if 1 parent has hypertension 45% chance, 2 parents =95% chance of developing. Proneness to bad cholesterol proile (ex. high ldl and total, low hdl) Also recall ldl is bad cholesterol, hdl is good. Can measure: total cholesterol 245 mg vs. 180mg/per 100 ml of blood 3. 4 x risk. Some foods high dietary cholesterol (meats, dairy, eggs) Other complex carbs may be okay (whole wheat, pasta)

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