HLSC 2P21 Lecture Notes - Lecture 17: Thymidine Triphosphate, Autoradiograph, Deoxyribonucleoside
15 Oct 2017
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Nucleosome position can be altered by chromatin remodeling complexes that move, eject, or replace nucleosomes: change how dna behaves in regards to nucleosomes itself called remodeling complexes. If the outcome is a direct result of the modification, such as making the chromatin structure more open, the modification is acting in cis. If the modification attracts another protein (blue) that performs the histone-modifying function, it is acting in trans. In order to move things around , neutralize interaction between histones and dna: modifications are inheritable because you are modifying residues which releases histones interaction with dna. *important for final exam: dntps: datp, dttp, dgtp, dctp (deoxyribonucleoside 5"-triphosphates) ( sugar-base + Blue strands are parental dna; red strands are new dna. The two replication forks proceed in opposite directions (bidirectionally) around the circular plasmid until they meet at the opposite side, forming two duplex circles: fragments created by adding primers (okazaki fragments) In eukaryotic cells these primers are rna, reinsert its influence.
