HLSC 1F90 Lecture Notes - Lecture 20: Anterior Pituitary, Growth Hormone Deficiency, Post-Translational Modification
31 Mar 2016
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Document Summary
Classical endocrine definition: chemical signals packaged in granules or secretory vesicles, secreted by a cell or group of cells, transported by blood, act on distant target tissues (receptors, activate physiological response at low concentrations (nanomolar to. Picture: hormones are secreted by endocrine gland or cells into the blood- only target cells with receptors for the hormone respond to the signal. Neurohormones: within the hypothalamus: are chemicals released by neurons into the blood for action at distant target, autocrine signals act on the same cell that secreted them, paracrine signals. Location of major endocrine glands: photo (don"t focus on female and male sex hormones) Typically as a measure of the time needed to decrease its concentration circulation by 50% Amino acid- derived or amine hormones (thyroid) Peptide or protein- is destine to get out of the endocrine cell, created a small sequence (signal) tells the newly formed peptide that it needs to be exported.
