HLSC 1F90 Lecture Notes - Lecture 4: Microorganism, Myasthenia Gravis, Innate Immune System
24 Feb 2015
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Document Summary
By the end of our lecture, we will be able to: explain the causes of and risk factors for infectious disease, describe how we defend ourselves against infection, justify vaccination for the prevention of infectious diseases. Income correlates with the ranking of infectious diseases as causes of death. Microbial classification: morphology what does it look like, physiology how does it sustain life, biochemistry what does it produce, molecular analysis nucleic acid signature. Risk factors for contracting infectious disease: the organism. Strength of the immune response: environment. Transmissibility: can i catch it? : direct contact human touch / contamination, airborne contact droplet transmission, autoinoculation. Pathogenicity: will it make me sick? : the ability of an infectious organism to cause disease, this may change with the condition of the host! Virulence: how sick will it make me? : a measure of disease severity, measurements. Tissue invasiveness: determinants virulence factors properties of the organism. Intracellular access (intracellular and facultative intracellular pathogens)
