HLSC 1F90 Lecture Notes - Lecture 7: Chemotherapy, Inflammatory Bowel Disease, Multiple Sclerosis

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Health Science 1F90 Tuesday, November 7, 2017
Lecture Seven
Addiction
A chronic disease that involves disruption of the brain’s systems related to reward,
motivation, and memory
It may start as a habit, but then become uncontrollable
It causes a pathological use of a substance or pursuit of behaviour in order to
relieve/avoid withdrawal
Historically, addiction was only recognized in relationship to drugs
Now, it is recognized that behaviours can be addictive
o For example, gambling, cell phones, etc.
For both drugs (substances) and behaviours, addiction has certain characteristics
Characteristics of Addiction
Reinforcement addictive behaviours reinforce themselves
o Positive the behaviour/substance use reliably results in pleasure or reward
o Negative being unable to engage in behaviour/use substance results in stress,
anxiety, discomfort, or depression
Compulsion or Craving there is a strong compulsion (irresistible need) to engage in the
behaviour/use substance
o Environmental cues trigger craving
o Obsessive planning for the next opportunity to engage
Loss of Control the individual cannot overcome the impulse to engage in the
behaviour/use the substance
Escalation more and more of the behaviour or substance is required to produce its
desired effects this is a result of tolerance
o Tolerance physical state in which the body adapts to a drug and the initial dose
no longer produces the original physical (body) or psychological (brain) effects
o Ex. Gambling, you want to gamble more with higher amounts
Negative Consequences the behaviour or substance use continues despite very serious
negative consequences
Risk Factors for Addiction
To understand risk factors, consider how an addiction develops…
o A person does something to bring pleasure or avoid pain
Drinks, goes online, gambles, shops, smokes, injects drugs
o If it works, the person repeats it (positive reinforcement)
o Tolerance develops (more of the behaviour/substance is required to get the
desired effect)
o Negative consequences emerge, but stopping seems unbearable due to
withdrawal symptoms
Risk of drug addiction depends on a combination of physical, psychological, and social
factors
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Document Summary

A chronic disease that involves disruption of the brain"s systems related to reward, motivation, and memory. It may start as a habit, but then become uncontrollable. It causes a pathological use of a substance or pursuit of behaviour in order to relieve/avoid withdrawal. Historically, addiction was only recognized in relationship to drugs. Now, it is recognized that behaviours can be addictive: for example, gambling, cell phones, etc. For both drugs (substances) and behaviours, addiction has certain characteristics. Reinforcement addictive behaviours reinforce themselves: positive the behaviour/substance use reliably results in pleasure or reward, negative being unable to engage in behaviour/use substance results in stress, anxiety, discomfort, or depression. Compulsion or craving there is a strong compulsion (irresistible need) to engage in the behaviour/use substance: environmental cues trigger craving, obsessive planning for the next opportunity to engage. Loss of control the individual cannot overcome the impulse to engage in the behaviour/use the substance. Gambling, you want to gamble more with higher amounts.

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