BIOL 2P93 Lecture Notes - Stroke Volume, Grey Matter, Aorta

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There are two types of cns circulatory regulation. Baroreceptors located in carotid sinus (glossopharyngeal n. ) and aorta (vagus n. ) Most sensitive in range of 60-120 mmhg. Ach onto muscarinic receptors on cardiac pacemakers slows depolarization and decreases heart rate. Arterial p baroreceptor discharge parasymp tone ach release pacemaker depol speed heart rate. Ne onto b 1 receptors on cardiac pacemakers speeds depolarization ( heart rate) and increases contractility ( stroke volume) Baroreceptor regulation controls arterial pressure within a wide range of pressures. Average level of baroreceptor regulation depends on activity (due to adaptation of stretch receptors) Baroreceptor regulation can dampen the effect of a perturbation by about 50%

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