BIOL 235 Lecture Notes - Lecture 8: Hyperinflation, Methacholine, Viral Disease
Document Summary
13. 4% of children <11 y. o. were diagnosed with asthma. Prevalence of asthma attacks has decreased from 51% - 39% of 0-11 y. o. Decrease in hospitalizations & er visits in developed countries. Childhood asthma rates highest in atlantic provinces, lowest in british columbia & prairie provinces. Most susceptible -> as a fetus & first 3-5 years of life. More than 100 genes have been discovered that play a role in the pathogenesis of asthma. Nlscy has found no correlation between household income & getting asthma and no correlation between living in a rural or urban area & getting asthma. Asthma is multi-modal & so usually is caused by more than one thing! Most people with asthma have a mix of both types. Intrinsic is not as well understood as extrinsic. We do know that involve inflammation that causes hyper responsiveness of the airways. Occurs within 10-20 mins of triggering stimuli & can last up to 2 hours.
