BIOL 204 Lecture Notes - Lecture 31: Succinate Dehydrogenase, Peripheral Membrane Protein, Mitochondrial Matrix

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Citric acid cycle has 8 enzyme-catalyzed reactions: 7 soluble enzymes in mitochondrial matrix, 1 enzyme bound to matrix side of inner membrane. Result of the citric acid cycle is: oxidation of acetyl group to co2, synthesis of atp, nadh and fad (reduced form fadh2, 1 acetyl-coa = 3 nadh, 1 fadh2, 1 atp, 2 molecules of co2 released, 3 h+, 1 coa (double this reaction since there were 2 acetyl-coa made from glycolysis) Purpose of etc and chemiosmosis is to extract the potential energy in nadh and fadh2 to synthesize more atp. Respiratory etc is a system of components found in eukaryotes on inner mitochondrial membrane, facilitates transfer of electrons from nadh & Complex i, iii, iv have prosthetic groups: prosthetic groups are redox active cofactors that alternate between reduced and oxidized states, it is not proteins that transfer electrons but the prosthetic groups, ex.

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