IMED2004 Lecture Notes - Lecture 36: Inflammatory Myofibroblastic Tumour, Endometrial Hyperplasia, Neoplasm
26 Mar 2020
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Review: growth disorders may be a response to stress or injury: Lecture 36: growth disorders: from yesterday"s lecture, hypertrophy: increase in cell/organ size. Not usually a risk factor for neoplasia: atrophy: decrease in cell/organ size. Not usually a risk factor for neoplasia: hyperplasia: increase in cell numbers. May be a risk factor for neoplasia (e. g. endometrial hyperplasia: metaplasia: change from one mature cell type to another. May be a risk factor for neoplasia (e. g. barrett"s oesophagus/goblet cell metaplasia/intestinal metaplasia of the oesophagus: today, dysplasia, neoplasia. Naming usually reflects the cells making up the mass: tumour = latin for swelling . Almost always means a neoplasm in common usage. E. g. hydrocoele, hernia, lymphoedema, inflammatory pseudotumour, abscess: tumours/masses that are not neoplasms, hamartoma. Mass formed of cells native to the tissue, but with a disorganised arrangement: ectopia. Normal tissue, usually normal architecture, but at the wrong site: components of neoplasm, neoplastic cells clonal, reactive stroma (connective tissue, blood vessels, often inflammatory cells)
