IMED1001 Lecture Notes - Lecture 3: Osteopathy, Nasolacrimal Duct, Myoglobin
Document Summary
Discuss the function of bone cells and bone and skeletal system. Understand the importance, distribution and maintenance of calcium in body. Discuss the hormonal control of calcium homeostasis. Bone: organs are protected by bone brain (by skull), heart and lungs (sternum and ribs), bladder, kidneys, gonads/uterus (pelvis), spine (protected by the vertebral foramen), does haematopoiesis (birth of blood) since blood inside the bone hence why its red. Muscles are connected to bone by ligaments and tendons. Storage (minerals-99% ca+2, lipids: protection (vital organs-cranial/thoracic, haematopoiesis (bone marrow) Hydroxyapatite- part that is left behind when ashes are formed. Osteogenic (start or birth: osteogenic progenitor cells- bone stem cells, need them to build bone (large numbers in uterus) and when bone is broken. Stem cells-proliferate then become osteoblasts: most active during bone growth but large numbers are reactivated in adult life in repair of fractures, also differentiate into osteoblasts during the continuous process of bone remodelling.