ANHB1102 Lecture Notes - Lecture 16: Adipose Tissue, Large For Gestational Age, Weight Gain

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2nd law of thermodynamics (everything moves towards increased disorder) Humans have self-replication to continue genes once deceased. Genome not a description of nal product just instructions (environment in uences nal outcome too). De nes a series of simple sequential steps. No xed nal product" ; ageing is continuous and inevitable. Montbeillard recorded height of his son throughout the 18th century; observed that when there was increased food supply (spring and summer) there was more increase in growth then in winter and autumn when food was low. Diurnal variation - height in the morning is slightly higher than that at night. Height sd is very small among populations. Weight gain occurs once peak height velocity has occurred (mid-pregnancy) - structure is in place so can start putting on weight. Leptin secreted from fat and signals to hypothalamus to reproductive system to being onset of puberty. Weight gain in early life (post-natally) is similar to that at puberty (or just prior).

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