PSYC1002 Lecture Notes - Lecture 10: Locus Coeruleus, Raphe Nuclei, Preoptic Area
19 May 2018
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Sleep and wakefulness
Nonadrenaline neurons in locus coeruleus
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Serotonin neurons in raphe nuclei
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Acetylcholine neurons in pons
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Disconnecting forebrain from brainstem causes profound and
almost continuous sleep
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Screen clipping taken: 4/11/2017 3:05 PM
Neurons active while awake and quiet during sleep
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Stimulant drugs have similar effects e.g. ecstasy,
amphetamines
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Electrical stimulation of neurons can wake a sleeping animal
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In brainstem certain neurons responsible for arousal
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Destruction of this area can cause insomnia, while stimulation
can induce sleep
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Neurons here contain GABA, which inhibit Ach, 5HT, NA arousal
systems in the brainstem
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Pre-optic area (anterior hypothal)
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Screen clipping taken: 4/11/2017 3:06 PM
What keeps you awake
L5 - sleep and wakefulness, feeding and appetite, reward
Saturday, 4 November 2017
1:23 PM
Neuroscience Page 1
Document Summary
L5 - sleep and wakefulness, feeding and appetite, reward. Disconnecting forebrain from brainstem causes profound and almost continuous sleep. Neurons active while awake and quiet during sleep. Electrical stimulation of neurons can wake a sleeping animal. Stimulant drugs have similar effects e. g. ecstasy, amphetamines. Destruction of this area can cause insomnia, while stimulation can induce sleep. Neurons here contain gaba, which inhibit ach, 5ht, na arousal systems in the brainstem. When awake, electrical activity in brains is high frequnecy and. When asleep, electrical activity in brain is characterised by slow rhythmic patterns ie. slow-wave sleep. Role of reciprocal connections between thalamus and cortex in orchestrating synchronised neuronal activity. At multiple times during the night, brain waves become desynchronised (like when we"re awake) During these periods eyes dart back and forth (rapid eye movement sleep, rem) If woken during rem, we typically report we were dreaming.
