MECH2901 Lecture Notes - Lecture 4: Beta Cell, Diabetic Nephropathy, Bone Resorption

• School: University of Sydney
• Department: Mechanical Engineering
• Course: MECH2901
• Professor: A/Prof Colin Dunstan

Document Summary

Explain the importance of intercellular communication, describe the mechanisms involved, and compare the modes of intercellular communication that occur in the endocrine and nervous systems. Understand the main organs of the endocrine system, contrast the major structural classes of hormones, and explain the general mechanisms of hormonal action on target organs. Describe the location, hormones and functions of the pituitary gland, and discuss the effects of abnormal pituitary hormone production. Describe the location, hormone and functions of the parathyroid glands, and discuss the effects of abnormal parathyroid hormone production. Describe the location, structure, hormones and functions of the pancreas, and discuss the effects of abnormal pancreatic hormone production. Understand the difference between endocrine and paracrine signalling. Understand the paracrine regulation of osteoclasts and how this interfaces with the parathyroid hormone endocrine signalling. Homeostasis keeping the whole body stable, growing and functional: chemically, nutritionally and sexually, requires cell to cell communication.