EXSS3023 Lecture Notes - Lecture 11: Leptin, Exercise Intensity, Sibutramine

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Revision: insulin sensitivity is reduced in obesity, weight loss significantly increases insulin sensitivity, strong relationship between insulin sensitivity & abdominal obesity. Recommendations for weight loss: who, obese adults (bmi >30) should lose weight, overweight adults (bmi 25-29) with comorbid conditions are only encouraged to lose weight, how much, 10% of initial body weight, how, lifestyle modification (behavioural weight control) Lifestyle modification: typically provide weekly individual/group treatment sessions designed to modify eating. & activity habits: comprise 3 components, diet, exercise, behavioural therapy. Reduction in weight and cardiovascular disease risk factors in individuals with. Diabetes care jun 2007, 30 (6) 1374- 383; doi: 10. 2337/ dc07- Long-term effects of a lifestyle intervention on weight and cardiovascular risk. Factors in individuals with type 2 diabetes mellitus four-year results of the look. The look ahead research group (2014), eight-year weight losses with an intensive lifestyle intervention: the look ahead study.

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