EXSS2028 Lecture Notes - Lecture 3: Succinyl-Coa, Acetyl-Coa, Electron Transport Chain
4 Sep 2018
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Document Summary
Beta = second carbon, alpha= first carbon. Fatty acids broken down 2 carbons at a time with an acid group. This cut of 2 carbons releases acetyl coa. = produces nahd molecule, fadh molecule (for the purpose of synthesizing atp), acetyl coa. Tca cycle: acetyl coa binds with oxaloacetate to produce citrate (via citrate synthase, a carbon is removed from citrate and released as co2. Nadh produced during process of removing carbon, as a hydrogen is released and attached to. Nad: another carbon is removed from alpha ketoglutarate as co2. => converted to succinyl coa: succinyl coa > succinate > fumarate > malate. During this fast process, gtp and atp are produced. Gtp (guanine triphosphate) is readily converted to atp during exercise: malate converted back to oxaloacetate and releases nadh. Are made when fat breakdown occurs with no insulin (starvation, exercise mimics) Synthesised from acetyl coa (hydroxybutyrate, acetoacetate, acetone)
