EXSS2022 Lecture Notes - Lecture 4: Royal Victorian Order, Glycogen, Mitochondrial Biogenesis

• School: University of Sydney
• Department: Exercise and Sport Science
• Course: EXSS2022
• Professor: Chin Moi Chow

Document Summary

2 m a x c e n t r a l. Peripheral (muscle) adaptations: central adaptations volume overload, eccentric cardiac enlargement, volume overload: end-diastolic sarcomeres in series (hypertrophy); increased lumen dimensions. Increased left ventricular edv: due to intensity & regular exercise, stimulates volume overload. Exercise intensity: hypervolemia (10 days), as much as 25, increased release of adh (absorb h2o into blood) & aldosterone (na+ reabsorption, increased plasma proteins, increased blood distribution to exercising muscle. Increased red cell count & haemoglobin (4wk-4mth): increase in o2 carrying capacity. Total protein: plasma proteins increase (linked to plasma volume) Increase in capillarisation: myoplasticity, skeletal muscles capacity for adaptive changes through changes in gene expression, results in alteration in structural, contractile & enzymatic proteins. 2 d i f f e r e n c e. Intracellular signaling for metabolic responses (et) ampk: muscle contractile activity causes , mechanical stretch, rapid increase in cytosolic & mitochondrial ca, metabolic changes dependent on relative exercise intensity.