HUBS1406 Lecture Notes - Lecture 11: Efferent Arteriole, Afferent Arterioles, Renal Pelvis
12 Oct 2018
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Nephron receives blood via the afferent arteriole, and blood leaves via the efferent arteriole. Not able to for through and therefore stays in the blood: How excess amino acids are broken down and excreted. Rate of excretion equals rate of production of nitrogenous wastes. If excretion decreases, the level of nitrogenous wastes in the blood increases. Drugs in the body once they have performed their function, they are delivered to the liver in a fat-soluble metabolite form. Some of these drugs are excreted in the faeces, however most of these are excreted via the kidneys. The fat-soluble metabolites must be converted into water-soluble metabolites in the liver to be excreted by the kidney. Some drugs are filtered out of the blood by the glomerulus, however most have to be removed via tubular secretion. Some drugs are reabsorbed once out of blood due to solute-solvent concentration gradient and urine-blood ph balance.
