PHRM3011 Lecture Notes - Lecture 8: Hyperlipidemia, Amlodipine, Oxprenolol
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Mercury sphygmomanometer (best using hand pump or stethoscope) or instrument. Drug history take both arms, not too tight, no exercise before, no caffeine before, smoking/alcohol, clothing in the way, arm not below heart. Age (older pts. on many drugs, pollypharmacy) Angiotensin ii antagonists (angiotensin receptor blockers) (arb"s) sartan or aria . Calcium channel blockers (ccb"s) pine 3 classes. Trial each change for > 6 weeks. Dose 12. 5-25mg = no effect on nephron. Se"s first dose hypertension: when pts has fluid loss, on diuretics, has diarrhoea if acei is added to diuretic tx. Acei and nsaids: bp could increase, kidney damage, triple whammy (acei or arb. Angioedema: swelling of face and tongue. Dry cough: pril cough , change to a arb if an issue. Kidney disease: monitor egfr ,25% below baseline and stabilises (2m) then continue, otherwise stop. May be used in hypertension (fluid in legs) Gestational ht onset > 20 weeks.