PHRM3011 Lecture Notes - Lecture 2: Cyp2B6, Suicidal Ideation, Bupropion
Document Summary
No craving with half an hour of waking. No smoking within first hour (nrt not therapeutic in this group) Up to 6 serious attempts before success. Stages of quitting: i don"t want to stop/quit, i have thought about it, i am planning to stop/quit, i am trying to stop/quit, i have stopped smoking but am afraid of relapse. Hand-mouth action taper from 6-12 cartridges/day over 8 weeks. Max 15/24hrs taper moderate to high dependence step down in four stages over 24 weeks. Gum chew slowly (10 bites) tingling or bitter taste = nicotine release: park gum in cheek till tingling goes chew again repeat for 30mins. Patches repeat every 1-2hrs titrate dose titrate dose side effects hiccups, tingling lip. Press against roof of mouth for 3 min to dissolve. Spray spray side of cheek repeat if craving after 2mins repeat every 0. 5-1hr prn. >10-15cigs/day: 12 week program, nicabate pre-quit patch.
