BIOL2202 Lecture Notes - Lecture 3: Stop Codon, Genetic Code, Start Codon
Document Summary
About the genetic code: the gene has initiation and termination codons for translation. Signals the start of translation and is the codon the first trna binds to. This first trna brings the amino acid met. Another regions coding for met that is not the first codon, has a different trna molecule. In prokaryotes: use gug and uug instead of aug as the start codon, this can only happen at the start. In mitochondria of vertebrates, drosophila and some fungi: aug codes for methionine instead of isoleucine. In mitochondria of drosophila: aga and agg codes for serine. In mitochondria of vertebrates: aga and agg code for stop, aga and agg code for protozoa instead of arginine. In candida species like candida albicans: cug code for serine instead of leucine. There are many deviations from the standard code in the mitochondria. This may be due to the endosymbiont theory. This fungi is the leading cause of life threatening fungal infection.
