BIOL1040 Lecture Notes - Lecture 13: Purkinje Fibers, Sinoatrial Node, Cardiac Muscle Cell

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22 Sep 2018
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Mod 4 - lecture 2: heart rhythm: some cardiac muscles are self-excitable. Can contract even though they do not receive signals from the nervous system: such excitable cardiac cells are called pacemaker cells (discuss later) Conduction through heart muscle: there are two types of heart muscle cells: pacemaker cells and non-pacemaker cells, pacemaker cells have spontaneously self-generating action potentials. Due to the presence of channels like ca+ that can cause depolarisation: pacemaker cells are connected to non-pacemaker cells via small connections called gap junctions, the action potential is transmitted to non-pacemaker cells via the gap junctions. How conduction works in heart: sinoatrial node (sa node) (the pacemaker cell) Determines the rate/timing of the cardiac muscle cell contractions. Located in the right atriu: atrioventricular (av) node: Impulses travel from sa to av node. The impulses are delayed when reaching av node (discuss later) Located also in the right atrium: purkinje fibres.

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