BIOL1020 Lecture Notes - Lecture 13: Epistasis, Natural Selection, Metagenomics
Document Summary
Real world genetics: textbooks tend to emphasise mendelian traits (e. g. single gene, dominant/recessive, recessive traits- usually a lack of normal function (because of a mutation) Incomplete dominant (e. g. pink flowers: could also be sex-linked traits, polygenic (e. g. skin colour, for a 3-locus trait- assume incomplete dominance with equal effect per locus, and no epistasis. Other continuous traits: shade of eye colour, pathogen resistance in rice. Is the study of continuous traits and their inheritance: phenotypic variation of a population is described as: If you have a phenotype and you want to find the genes contributing to that phenotype. Molecular markers show which parent the chromosomal blocks come from: usually many loci are identified that contribute to continuous traits, e. g. Summary: most phenotypic traits are affected by both environment and genetics, and have a polygenic basis, associations between phenotypes and genetic loci can be determined using both traditional breeding experiments and large scale genomic surveys.
