BABS1201 Lecture Notes - Lecture 8: Lipid Bilayer, Facilitated Diffusion, Membrane Transport

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scarletdolphin313

18 Nov 2018

School

UNSW, UNSW Sydney

Department

Biotechnology & Biomolecular Sciences

Course

BABS1201

Professor

john

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Document Summary

The phospholipid bilayer is impermeable to most molecules. But the cell needs energy, building blocks for its components, cofactors, etc. , which are outside of the cell. In facilitated diffusion, transport proteins assist movement of molecules down a concentration gradient; requires no energy input. Channels: conduits allow direct passage from one side of the membrane to the other. Carriers: binding of solute on one side of membrane produces conformational change in protein moving solute through. Channels: integral membrane proteins, which allow diffusion across membrane down a concentration gradient. Channel proteins provide a corridor for specific molecules or ions to cross the membrane. Water can diffuse across the membrane - but only very slowly because it is polar. Aquaporins are the specific channel proteins for water. Allows the cell to take up and retain the molecules it needs and exclude what is unwanted.

Related Questions

Read the following scenarios and indicate which of the following processes they describe.

11. Sodium molecules move randomly around a solution of sodium chloride in water, frequently colliding with other sodium ions and chloride ions. secondary active transport diffusion osmosis facilitated diffusion primary active transport

12. Sodium ions (Na+) move through sodium channels in a synthetic membrane. primary active transport secondary active transport facilitated diffusion osmosis

13. Water molecules move into the cytosol of a cell placed in a hypotonic solution. primary active transport secondary active transport facilitated diffusion osmosis

14. Water molecules move into the cytosol of a cell placed in pure water. facilitated diffusion osmosis secondary active transport primary active transport

15. Water molecules move out of a cell placed in a hypertonic solution. facilitated diffusion primary active transport secondary active transport osmosis

16. The action of sodium-potassium pumps moves sodium ions (Na+) out of a cell and potassium ions (K+) into a cell. facilitated diffusion secondary active transport osmosis primary active transport

17. Glucose molecules move into cells lining the intestine against their concentration gradient driven by the movement of sodium ions (Na+) into the cells down their concentration gradient. osmosis secondary active transport primary active transport facilitated diffusion

18. A beaker of water is separated by a selectively permeable membrane that allows the passage of water but not ions. A solution of 4% sodium chloride (NaCl) is placed on one side of the membrane and pure water is placed on the other side of the membrane. The solutions are allowed to equilibrate. At this point, which process is going on? facilitated diffusion osmosis secondary active transport primary active transport

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Question 1

Plasma membranes are selectively permeable. This means that

	A.	glucose cannot enter the cell.
	B.	the plasma membrane allows some substances to enter or leave a cell more easily than others.
	C.	plasma membranes must be very thick.

Question 2

Oxygen molecules O₂ crosse a plasma membrane by

	A.	passive transport
	B.	osmosis
	C.	active transport

Question 3

Facilitated diffusion across a biological membrane requires ________ and moves a substance ________ its concentration gradient.

		A. energy and channel proteins; against (up)
		B. transport proteins that make channels ; down
		C. energy ; down

Question 4

When two aqueous solutions that differ in solute concentration are placed on either side of a semipermeable membrane and osmosis is allowed to take place, the water will

		A. move to the side with lower water concentration
	B.	move to the side with higher water concentration
	C.	move to the side with lower solute concentration

Question 5

Kinetic energy differs from chemical energy in that

	A.	chemical energy is a particular form of kinetic energy.
	B.	kinetic energy is the energy of a moving object, whereas chemical energy is the potential energy of molecules.
	C.	kinetic energy is stored energy that has the potential to do work, and chemical energy is the energy of movement.

Question 6

When a cell uses chemical energy to perform work, it uses the energy released from a(n) ________ reaction to drive a(n) ________ reaction.

	A.	exergonic; endergonic
	B.	endergonic; exergonic
	C.	spontaneous; exergonic

Question 7

When an enzyme catalyzes a reaction

		A. it raises the activation energy of the reaction.
		B. it lowers the activation energy of the reaction.
		C. it is used once and discarded.

Question 8

Which of the following statements regarding enzyme function is false?

		A. An enzyme's function depends on its three-dimensional shape.
		B. Enzymes are very specific for their substrates.
		C. Enzymes are used up when they catalyze a chemical reaction so must be synthesized for each new chemical reaction

Explain the cell theory; know the three basic tenets of the theory.

All cells have to carry out certain functions, what do all cells have in common?

Compare/contrast an Eukaryotic vs a Prokaryotic cell type.

Understand the concept of selective toxicity. What do all effective targets of an antimicrobial agent have in common? What are some characteristics of Prokaryotic cells that can be targeted?

Explain the unity and diversity of prokaryotic cells in terms of evolutionary theories.

Describe the three basic shapes (morphologies) of bacteria.

What are the functions of the plasma membrane, how does the structure of the plasma membrane aid in carrying out these functions?

Describe the fluid mosaic model of the plasma membrane. Draw out the plasma membrane, include the phospholipid bilayer (indicating polar/hydrophilic and nonpolar/hydrophobic components) and peripheral and integral proteins. Also indicate the intracellular (cytoplasmic) and extracellular regions.

What are the functions of the components of the plasma membrane? Phospholipids, proteins?

Transport. Compare/contrast the following mechanisms of transport in terms of the types of molecules transported, with or against the concentration gradient, if any Energy input is required, if a transport molecule is involved, and if Euk and or Prok use this mechanism.

Osmosis (explain the role of aquaporins)

Diffusion

Facilitated Diffusion

Active transport (proton motive force / ATP binding cassette system)

Group translocation

BABS1201 Lecture Notes - Lecture 8: Lipid Bilayer, Facilitated Diffusion, Membrane Transport

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