BABS1201 Lecture Notes - Lecture 8: Conformational Change, Macrophage, Phagocytosis

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Lecture 8 - 23/03/18 - nutrient and ion transport. The phospholipid bilayer is impermeable to most molecules: but the cell needs energy, building blocks for its components, cofactors etc which are outside the cell, proteins play an important role in transport. Passive transport - no energy required: diffusion, facilitated diffusion, passive transport aided by proteins. In facilitated diffusion transport proteins assist the movement of molecules down a concentration gradient; no energy input: channels, conduits allow direct passages from one side to the other. Concentration gradients: differences in ion concentrations inside and outside cells, they are maintained by active transport against the gradient will disappear with time if they are not maintained. Irreversible: transport is directional, the energy released by atp allows hydrolysis, active transport - one molecule, active cotransport - two molecules, plants, the return of h+ to the cytosol down a con gradient drives the uptake of sucrose.

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