BABS1201 Lecture Notes - Lecture 11: Redox, Ethanol Fermentation, Atp Synthase

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BABS1201 Notes LEC 11
LEC 11: Metabolism II
Cellular respiration is what produces ATP
CELLULAR RESPIRATION: Glycolysis:
Carbohydrates glucose
o E.g. starch is broken down by amylase into glucose monomers
Glycolysis: breakdown of glucose into 2 molecules of pyruvate
o Investment stage: 2 ATP are consumed for 1 glucose, glucose is converted to
form 1 (6 carbons) and then to form 2 (3 carbons)
Adding energy (ATP consumed)
o Harvesting stage: 4 ADP 4 ATP and 2 NAD+ 2 NADH to convert form 2
into pyruvate which is the removal of a phosphate group (Pi)
Net gain of 2 ATP
Generating energy (ATP created)
Oxidation of pyruvate into acetyl-CoA: transition stage before TCA cycle
o For one pyruvate molecule: 2 NADH generated, 2 CO2 released by PDH
TCA cycle: Generates the reducing agents NADH and FADH2 for electron transport
chain function
o 8 enzymes used to oxidise acetyl-CoA
o Reduced: NAD+ NADH and FAD FADH2
o CO2 waste product
Oxidative phosphorylation and chemiosmosis: NADH and FADH2 provide electrons
to establish a proton gradient across a membrane, where a proton motive force
drives protons through the ATP synthase channel to generate ATP.
Investment stage
Harvesting stage
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