PSY3320 Lecture Notes - Lecture 4: Melanopsin, Neuropeptide Y, Corticosterone
15 Oct 2018
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Master circadian clock but all our tissues can tell the time > want a master oscillator (pacemaker) Light is the major input, we want our master clock to be synchronised to light/dark cycle. Silk moth and cockroaches have clock localisation. Drosophila eclose at different times of day even in constant darkness therefore it must be controlled by a clock. Truman removed the brain from drosophila > eclosed at random times. Did truman remove the underlying mechanism of the clock or just the animal(cid:1685)s ability to express it. Truman (1970) studied 2 species of silk moth with different eclosion times, performed a brain transplant between the two species. Found: the moths swapped eclosion times suggesting the clock is in the brain of the moth. Cockroaches: remove eyes of the cockroaches > free run therefore clock isn(cid:1685)t in the eyes. Removal of optic lobes (in the brain) > arrhythmic activity suggesting the clock is in the brain.
