PSY3130 Lecture Notes - Lecture 7: T Helper Cell, Catecholamine, Gonadotropin-Releasing Hormone
15 Sep 2018
School
Department
Course
Professor
Document Summary
What are the releasing and inhibiting factors of the hypothalamus. Corticotropin releasing hormone (crh), luteinizing hormone releasing hormone (lhrh), thyrotropic releasing hormone (trh), growth hormone releasing hormone (ghrh), growth hormone inhibiting factor (ghif), dopamine. Milk ejection, uterine contraction during labour, role in bonding. Bound to large proteins, inclduing corticosteroid binding globulin (cbg) and albumin , and carried in the body through the blood. Mineralcorticoid receptors: high affinity for aldosterone and endogenous glucocorticoids. Glucocorticoid receptor: low affinity for endogenous glucocorticoids, high affinity for dexamethasone. How do steroid hormones act in terms of binding. After binding, the receptor moves into nucleus and regulate gene transcription. Driven by signals from hypothalamus, highly sensitive to negative feedback control. Secretion enhanced by input from amygdala, negative feedback less effective. Serves to discriminate self from non-self, destroy and clear foreign substances, ignore self, possibly destroy altered self. Any substance that can be identified as immune. Microorganism that can cause disease when they enter.
