BMS2021 Lecture Notes - Lecture 10: Adult Stem Cell, Sensory System, Cellular Differentiation
15 Aug 2018
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Define the terms totipotency, pluripotency and unipotency and gives examples. Cell potency: ability to differentiate into other cell types. Greater potency = can differentiate into more cell types. Totipotent: capable of giving rise to any cell type or (of a blastomere) a complete embryo. Pluripotent: capable of giving rise to several different cell types. Multipotent: capable of self-renewal by dividing and developing into multiple specialised cell types present in a specific tissure or organ. Unipotent: capable of giving rise to only one cell type. Describe the formation of the early human embryo the blastocyst. Cleavage: period of rapid cell division (without growth) following fertilisation. Morula: cells of compacted embryo divide (ball of cells; outer and inner cells) Blastocyst: inner cells moved to one side, cavity forms (inner cell mass + trophoblast) Inner cell mass is the source of embryonic stem cells ( = es cells)
