BMS1052 Lecture Notes - Lecture 11: Edge Detection, Trpv1, Axon Hillock
18 Aug 2018
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Identify the properties of mechanoreceptors in the skin ( eg: location, receptive field size, adaptation rate) Describe the stimuli that each mechanoreceptor is optimised to process, based on its response properties. Describe the functional organisation of the somatosensory cortex, and how it relates to touch perception. Describe how cortex can reorganise depending on sensory experience. Mechanoreceptors - peripheral touch receptors ( ie energy transductors - physical -> electrical) Membrane tension or stretch can open up ion channels. In somatosensation, the channels that open in response to this are na channels, that cause depolarisation of the membrane. Direct activation through lipid tension ( stretching of membrane etc. ) The protein may be linked intracellularly to the cytoskeleton and extracellularly ( linked to the surrounding tissue) Indirect action through membrane structural proteins the effect of physically gated g - protein coupled proteins will be slow to activate and long lasting note the yellow signalling molecule in the picture.
