PSYC20006 Lecture Notes - Lecture 9: Nocebo, Midbrain, Acetylcholine

• School: University of Melbourne
• Department: Psychology
• Course: PSYC20006
• Professor: Stefan Bode

Document Summary

Receptors: located on outside of cell membrane, embedded. Involved in what can enter/exit cell: 2 types: Ions then flow through: g-protein, e. g. calcium ion channel, single polypeptide folded into a globular shape, embedded in cells membrane, when an external molecule binds to a gpcr, it causes changes. Gdp (if protein is inactive: at binding, the g protein breaks off into 2 parts gtp-bound alpha subunit and beta-gamma dimer. Neurotransmitter vs. neuromodulators: neurotransmission, either excitatory or inhibitory, occurs at a specific synapse during direct synaptic transmission, excitatory: Inhibitory: decreases firing of next neuron, neuromodulation, slightly slower processes, subset of neurotransmitters, neuron uses one or more chemicals to regulate populations of neurons. Neurotransmitters: excitatory: glutamate, released by all excitatory neurons, found in long projection neurons throughout cortex, acts on: Ion channels: g protein-coupled receptors, excitatory connections are point to point", have region specific functions.