PSYC20006 Lecture Notes - Lecture 21: Partial Seizure, Entorhinal Cortex, Etiology

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Hm & the anatomy & function of the temporal lobes. Hm (henry molaison: died in 2008 (age 82, most studied patient in history of neuroscience (corkin, 2002, 1953: 27 y/o man with severe temporal lobe epilepsy, september: underwent bilateral resection of extensive amount of medial temporal tissue. Involves many brain regions: temporal lobes (tl) are engine" of memory, functional asymmetry. Epilepsy: epileptic seizures arise from sudden excitation in groups of neurons with a loss of inhibitory potential. Intermittent derange of the nervous system due presumably to a sudden, excessive, disorderly discharge of cerebral neurons. (adams, victor & Inhibitory-excitatory balance: gaba & glutamate: excitatory synapse, nt glutamate, action: increases spread of excitation. Inhibitory synapse, nt gaba, action: increases nervous system stability: temporal lobe epilepsy (tle) Retrograde vs anterograde amnesia: retrograde: impairment for memories created prior to injury, anterograde: impairment for memories created after injury; impairment in learning novel info.

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