PHYS20008 Lecture Notes - Lecture 33: Intramuscular Injection, Glut4, Intramuscular Fat
Document Summary
Lecture 33: adaptations to training and the effect of heat - 28/05/19. Aim is to produce progressive overload / adaptation considerations include: intensity how hard, duration for how long, frequency how often, mode specificity of training, rate of progression. Training response stimulus fatiguing exercise -> reduction in whatever is happening -> in response to stress you activate a number of systems compensation. Transient alterations in gene expression contribute to skeletal muscle exercise adaptations. Repeated endurance training improved glycogen storage increased intramuscular triglyceride storage: provides more substrate for utilization during prolonged exercise increase glut4 expression, enhances capacity for glucose uptake into cell increased mitochondrial capacity. Mitochondrial biogenesis is a key adaptation to training. After 12week, the exercisers were running continuously for 2 hr day, 5 days/wk, up an 8 degree incline at 31m/min with twelve 1 min intervals of running at 42m/min interspersed through the work period. Enzymes of etc increased way more in exercising animal.