PHYS20008 Lecture Notes - Lecture 12: Myocyte, Actin, Ion
23 Jul 2018
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Actin and myosin filaments make it striated. Pa(cid:272)e(cid:373)aker at apex is the origin and propagates it. Pacemaker cells in the nodes are the spontaneous rhythmic electrical signals through intercalated discs to the top. Cardiac glycosides- in reducing the sodium gradient it will slow down 9 so calcium is slower to drain so more calcium in cell= harder contraction (causes more damage in the long term) The unstable resting potential due to cation leak will cause spontaneous reaching of threshold. May or may not be individually innervated depending on location. Actively stimulate myosin then holds the contraction until we actively dephosphorylate the (cid:373)yosi(cid:374) to tell it to release. Skeletal muscle are dependent on sodium and potassium. Skeletal (cid:373)us(cid:272)le just (cid:374)eeds ap through t tu(cid:271)ule. Has it"s o(cid:449)(cid:374) (cid:272)al(cid:272)iu(cid:373) i(cid:374) sr so does(cid:374)"t (cid:374)eed e(cid:272)f. Last two need ecf to stimulate release more from sr.
