NEUR30003 Lecture Notes - Lecture 20: Metabotropic Glutamate Receptor 1, Metabotropic Glutamate Receptor, Adenylyl Cyclase
11 Aug 2018
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Document Summary
* the molecular mechanisms involved in memory involve 2 processes: long term potentiation and long term depression. * in theoretical analysis of memory, one of the major ways that memories can be formed is by the strengthening and weakening of synapses when the neurons are active and when the connections between them are active. When the connections between neurons are active, then you get strengthening of the synapses. When only the input is active, and the output is not, you get weakening of that connection. All of these sorts of memories are stored atleast in part in the strength and weakness of synaptic connections within the distributed network of neurons. * long term activity dependent plasticity that satisfies criterion that synapses strengthen when pre. And post-synaptic neurons are active at the same time long term potentiation (ltp). Thus, strengthening the connections would lay down a pattern of activity that ultimately would form an associative memory.
