NEUR30003 Lecture Notes - Lecture 3: Neurotransmitter Receptor, Dendritic Spine, Granule Cell

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We now know there is a discrete step that is called the synapse, but for many years it was difficult to say what happened when a nerve met its target, and how the signal got across. Therefore, in some cases, the two divisions (sympathetic & parasympathetic) oppose each other and how could this be if electrical impulses came down and fused with the heart, how can some of these be excitatory and some be inhibitory. * the idea of a chemical connection had been around for quite some time. 1850s people had started saying that one of the reasons that certain chemical compounds work is that maybe there is a chemical step somewhere in neural transmission. *the b(cid:396)itish ph(cid:455)siologist cha(cid:396)les he(cid:396)(cid:396)i(cid:374)gto(cid:374) suppo(cid:396)ted the neu(cid:396)o(cid:374) do(cid:272)t(cid:396)i(cid:374)e e(cid:448)e(cid:374) (cid:271)efo(cid:396)e cajal"s evidence convinced the scientific establishment to abandon the reticular theory (he thought that neurons were distinct entities that must have a means of communicating with each other).

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