GENE20001 Lecture Notes - Lecture 5: Epistasis, Wild Type

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In the heterozygote, if we get complementation we know the parents are recessive. When the snake is orange it is producing orange pigment, it is not producing black pigment which means it is mutated in the o gene. When we are unable to produce a particular gene product, we get the orange phenotype and the gene is called orange. The camouflaged snake is producing both pigments and it has a camouflaged phenotype. Doesn"t matter if it is heterozygous or homozygous as long as it has one wild type copy of each gene. The black gene produces the orange pigment and this is because we name it after the mutant phenotype. What we are seeing is a synthetic interaction. This is how we say whether it is a synthetic or a genetic interaction. When the yellow mutant is crossed with the green mutant we are going to get all red as complementation occurs as the genes are different.

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