GENE20001 Lecture 25: 25 Population Genetics
Document Summary
Population genetics is an extension of mendel"s laws of inheritance, molecular genetics and the ideas of darwin. All alleles of every gene in a population make up the gene pool. Only individuals that reproduce contribute to the gene pool of net generation. Population geneticists study genetic variation in gene pool and how it changes. Population: group of individuals of the same species that can interbreed. Composed of smaller subpopulations (local populations or demes). Members of subpopulation far likelier to breed with each other. Subpopulations often separated by geographic or ecological barriers. Immunological markers: e. g. different blood groups (different antigens) Allozymes: two or more enzymes encoded by same gene with alterations in amino acid sequence. Alleles of same gene that encodes an enzyme. Detects amino acid substitutions which lead to charge changes (about 30% of all amino acid substitution). Because of these limitations we don"t tend to use this method anymore.
