GENE20001 Lecture Notes - Lecture 11: Zygote, Restriction Site
Document Summary
Transmission of organelles is not always through maternal inheritance. If results of genetic crosses do not conform to mendelian predictions then suspect extra- nuclear inheritance. But it may be due to something else. Mendelian ratios not observed because meiosis-based mendelian segregation is not involved. Results of reciprocal crosses involving extra-nuclear genes differ from reciprocal crosses involving nuclear genes. Extra-nuclear genes generally show uni-parental inheritance (often maternal) Extra-nuclear genes cannot be mapped to nuclear chromosomes. Non-mendelian inheritance is not affected by substituting a nucleus of a different genotype. This shows the d allele was transmitted and that this is not maternal inheritance. Only applies to genes that have an effect on early development and have gene product in eggs. Probs not aut rec as it relies on people marrying in being heterozygous and generation iii is not likely. Genetics page 7 b) c) d) e) f)
