GENE20001 Lecture Notes - Lecture 6: Sex Linkage, Wild Type

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29 Jun 2018
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Drosophila, 2 mutant phenotypes vg, e are autosomal recessive. vg trait on second
chromosome whereas e trait on third. Homozygous males vg, e, mated to homozygous
wildtype females. Males in this cross homozygous for translocation between 2nd and
3rd chromosomes. The vg and e loci included on the translocated sections of the two
chromosomes. F1 males then backcrossed to homozygous vg, e females.
2010 Q22
Genetics Page 4
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Document Summary

Drosophila, 2 mutant phenotypes vg, e are autosomal recessive. vg trait on second chromosome whereas e trait on third. Homozygous males vg, e, mated to homozygous wildtype females. Males in this cross homozygous for translocation between 2nd and. The vg and e loci included on the translocated sections of the two chromosomes. F1 males then backcrossed to homozygous vg, e females. Tip for translocation questions is to make a diagram. These gametes are mated with v e female gametes. Male contains a heterozygous translocation, breakpoint on 2nd chromosome in, or very near, the vg gene. This male is mated with a female homozygous vg normal chromosome arrangement), all male offspring are vg, while all female offspring are wt. Sex linkage involved, the other chr must be x or y. This means that the chromosome involved in the translocation are the second chromosome and: x chromosome.

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