BIOM30001 Lecture Notes - Lecture 15: Tissue Engineering, Transplant Rejection, Organ Transplantation
Document Summary
Require human donor (low incidence of organ donors in aus) Transplant rejection can damage other functional and healthy tissues. Exciting, new, innovative, multidisciplinary field scientists, clinicians, engineers bioengineering/material science, chemistry, biology, medicine. Biological approach: alternative to traditional surgical procedures including organ transplantation, reconstructive surgery, and prosthesis. Tissue engineering is the process of growing new tissues and organs for the maintenance/repair/improvement/replacement of damaged, diseased, or poorly functioning tissues or organs, e. g. due to trauma/birth defects/cancer/disease. Regenerative medicine more specifically refers to the application of stem cells to regrow tissues and organs. Epicel: single layer of keratinocytes that are autologous (come from the patient). Can be placed over burn wounds that are too large to heal on their own. Dermal regeneration template: non-cellular, provides physical barrier of collagen i, chondroitin (derived from shark) and silicon sheet (protective layer) But these are easy because this tissue is thin and flat.
