BCMB20002 Lecture Notes - Lecture 12: Maurice Wilkins, Francis Crick, The Double Helix

• School: University of Melbourne
• Department: Biochemistry and Molecular Biology
• Course: BCMB20002
• Professor: Terry Mulhern

Document Summary

All figures from lecture 12 slides of h. verkade, melbourne university, march 2017 (unless stated) Dna based content is different between species, the same all over one organism, and does not vary over time or environment. The number of a always equalled number of t. The number of c always equalled number of g. Chemically analysing chromosomes from different species (first isolate chromosome, then isolate. Cell can use complementary pairing to constructs both strands. Hence only 1 strand code needs to be known. Part of dna and rna (amp or damp) Atp rna nucleotide (atp or datp) Double strand is the same width all the way. Bases are connected with a phosphodiester bond. The 5(cid:859) a(cid:374)d 3(cid:859) is very very i(cid:373)porta(cid:374)t. Main chain are linked covalently, and very strongly. However, bases are linked h-bonds, and not strong. Only one strand code is needed to be known, to know the whole structure stronger than at bonds.