HBS101 Lecture Notes - Lecture 9: Alveolar Cells, Pulmonary Surfactant, Respiratory Tract

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28 Feb 2019
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Function of the respiratory system: major function-respiration. Supply body with o2 for cellular respiration; dispose of co2, a waste product of cellular respiration. Four processes involve both respiratory and circulatory systems. External respiration-o2 and co2 exchange between lungs and blood. Respiratory system: pulmonary ventilation (breathing)-movement of air into and out of lungs. Internal respiration-o2 and co2 exchange between systemic blood vessels and tissues. Functionally there are two zones: conducting zone, respiratory zone. Each structure has protective features like hairs, cilia, glands for mucous, macrophages etc. Major structures: nose, nasal cavity, pharynx, bronchi and their branches, air flows through each structure and onto the next structure in line. Respiratory zone: respiratory bronchioles, alveolar ducts, alveolar sacs (clusters of alveoli, main site for gas exchange. Respiratory membrane: alveolar and capillary walls and their fused basement membranes, 0. 5- m-thick; gas exchange across membrane by simple diffusion, extremely thin, but large surface area (approx.

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