BM1022 Lecture Notes - Lecture 12: Cryoprecipitate, Blood Type, Thalassemia
Document Summary
Explain the abo and rh blood grouping systems. Loss of over 30 percent causes shock, which can be fatal. Transfusions are the only way to replace blood quickly. Transfused blood must be of the same blood group. Those whose red blood cells do not function adequately. People experiencing severe bleeding such as accident victims and patients undergoing surgery. Used to help clot blood and seal wounds in surgical and cancer patients. Leukaemia and chemotherapy treatments can reduce a patients platelet count. Used to make a number of different products. Red blood cells have antigens on their surface. Abo system: a antigen, b antigen, o = neither. Rhesus antigen: rh+ or rh- (aka rhesus-d or d). Others include c, c, e, e, duffy, kidd and kell. Transfused rbcs may be recognised as foreign and attacked if rbc antigens of donor and recipient don"t match. Based on the presence or absence of two antigens.
