BM1022 Lecture Notes - Lecture 14: Norman Heatley, Artemisinin, Louis Pasteur
Document Summary
Describe how antimicrobials kill or inhibit growth of microorganisms. Explain how resistance can develop to antimicrobial drugs. Inability to control an infection can be life-threatening. Use of drugs to kill or inhibit microorganisms. Use of antigens from a specific microbe to generate a protective immune respon. 1874 - louis pasteur and others noticed some microbes could inhibit the growth of oth. 1940s - howard florey, ernst chain and norman heatley purified penicillin and develop methods to produce large enough quantities to allow it to be used as a treatment. Compounded by a microorganism that in small amounts can kill or inhibit anothe microorganism. A compound that is able to kill, or inhibit the growth of, a microorganism. Can be natural (antibiotic) or synthetic (sulfa drugs). Antimicrobial that inhibits the growth of an organism. Range of activity of an antimicrobial against an organism. Broad spectrum antibiotics are effective against a wide variety of organisms.
